Profhilo Profhilo is a unique formulation of hyaluronic acid that can stimulate all FOUR types of collagen and elastin formation. It is a super skin booster and a superb product to improve the radiance and youthful glow of your skin. It contains a mixture of low and high molecular weight hyaluronic acid which allows it to both boost skinhealth and appearance AND improve support in the deeper structure of your skin. Profhilo treatment is administered in two sittings, the price is £350 and £300 respectively. Profhilo skin remodeling with a unique hyaluronic acid Profhilo is developed by using a patented technology resulting in hybrid cooperative complexes between high molecular weight HA and low molecular HA without the use of any chemical cross-linking compounds. These complexes increase the stability of HA to enzymatic and mechanical degradation. What is hyaluronic acid (HA) ? HA naturally occurs in your skin and, along with other essential skin components, such as collagen, decreases with age. Skin aging is a multifactorial process consisting of two distinct and independent mechanisms: intrinsic and extrinsic aging. Youthful skin retains its turgor, resilience and pliability, among others, due to its high content of water. Daily external injury, in addition to the normal process of aging, causes loss of moisture. The key molecule involved in skin moisture is hyaluronic acid (HA) that has unique capacity in retaining water. There are multiple sites for the control of HA synthesis, deposition, cell and protein association and degradation, reflecting the complexity of HA metabolism. The enzymes that synthesize or catabolize HA and HA receptors responsible for many of the functions of HA are all multigene families with distinct patterns of tissue expression. Understanding the metabolism of HA in the different layers of the skin and the interactions of HA with other skin components will facilitate the ability to modulate skin moisture in a rational manner.